AGA - PCOS
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PCOS is a condition involving insulin resistance, increasing in
oxidative stress and inflammation that leads to altered metabolism
and relative hormonal imbalance resulting in hair loss.
Cyclical nutrient therapy helps to build up the immune system and counters inflammation. It restores cellular function and supports overall recovery. - The excess secretion of androgen in PCOS patients contributes to androgenic alopecia, acne, hirsutism and menstrual disorder.
- AGA is described as prolongation of telogen and shortening of anagen. Clinically, every alopecia begins as simple hair fall or telogen effluvium. Continued exposure to these non androgenic factors, promotes gradual cellular dysfunction and accumulation of ROS, which is proven to increase the sensitivity of androgen receptors (AR) making them hyper sensitive to normal circulating androgens, without any rise in androgen levels.
- ROS also trigger the release of inflammatory cytokines which further augment various AR sensitive pathways. Thus, the follicles have now become sensitive to normal androgens and DHT from relentless exposure to non androgenic factors.
- In conditions of nutrient deficiencies, the body prioritizes short-term survival over long-term health through physiological triage. Evident in redistribution of blood flow to the vital organs in conditions of low oxygen pressure or shock. Triage prioritizes ATP synthesis over DNA-repair, erythrocyte function over leukocytes and neuroendocrine functions over liver enzymes. The high metabolic demand of the hair follicle is subject to triage even under marginal nutrient deficiencies.
- Hair growth is compromised to divert nutrients towards more important systems. The diversion maintains normal nutrient levels in circulation by compensating the deficiencies.
Key Ingredients & Roles
With advantages of ingredients Myoinositol, Curcumin,
Quercetin, Pumpkin seed extract, Omega 3 fatty acids etc.
Myo- inositol
It reduces hyperandrogenism and dyslipidemia through the
reduction of plasma insulin levels. It promotes glucose uptake
and glycogen synthesis in the liver.
Quercetin
It suppresses insulin resistance, reduces testosterone,
luteinizing hormone (LH) and FSH follicle stimulating hormone in
pcos. It stimulates hair growth with enhanced expression of
growth factors via activation of MAPK/CREB signaling pathway.
Curcumin
It improves menstrual irregularities women with pcos works as
anti-inflammatory and antioxidant. Curcumin lowers DHT levels by
blocking the action of the 5 alpha reductase enzymes.
Pumpkin seed
extract
It contains beta –sitosterols which blocks the conversion of
testosterone to DHT. It also helps to balance androgen level and
prevents symptoms of acne and excessive hair growth.
Omega 3 fatty acids
It works as anti-inflammatory and improves insulin resistance
patient with pcos. It promotes hair thickness and length.
Contact
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